Published October 15, 1978
| Version v1
Journal article
Heavy metal binding to biological molecules
- 1. Oxford Univ. (UK). Inorganic Chemistry Lab.
- 2. Howard Univ., Washington, DC (USA). Dept. of Chemistry
Description
The substitution of mercury into the metal chelating antitumour drug bleomycin and the metallo-enzyme superoxide dismutase (EC 1.15.1.1.) is described with the observation of coupling between the 199Hg nucleus (I = 1/2) and the protons on the coordinating histidyl groups. (Auth.)
Additional details
Additional titles
- Subtitle (English)
- Identification of ligand by observation of "1"9"9Hg - "1H coupling
Publishing Information
- Journal Title
- FEBS (Fed. Eur. Biochem. Soc.) Lett.
- Journal Volume
- 94
- Journal Issue
- 2
- Series
- FEBS (Fed. Eur. Biochem. Soc.) Lett.
- Journal Page Range
- 311-314
- ISSN
- 0014-5793
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 10432303
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- BLEOMYCIN; CHELATES; CHEMICAL SHIFT; COUPLING; HYDROGEN 7; LIGANDS; MERCURY; MERCURY 199; NUCLEAR MAGNETIC RESONANCE; PROTONS
- Descriptors DEC
- ANTIBIOTICS; ANTIMITOTIC DRUGS; BARYONS; CATIONS; CHARGED PARTICLES; COMPLEXES; DRUGS; ELEMENTARY PARTICLES; ELEMENTS; EVEN-ODD NUCLEI; FERMIONS; HADRONS; HEAVY NUCLEI; HYDROGEN IONS; HYDROGEN IONS 1 PLUS; HYDROGEN ISOTOPES; INTERNAL CONVERSION RADIOISOTO; IONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; MAGNETIC RESONANCE; MERCURY ISOTOPES; METALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; NUCLEONS; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; RADIOISOTOPES; RESONANCE; STABLE ISOTOPES