Published September 1978 | Version v1
Journal article Metadata-only

Fractionated radiation treatment combined with hyperthermia in transplantable adenocarcinoma of the mouse

Creators

  • 1. Muenchen Univ. (Germany, F.R.). Strahlenbiologisches Inst.
  • 2. Gesellschaft fuer Strahlen- und Umweltforschung m.b.H., Neuherberg (Germany, F.R.). Inst. fuer Biologie

Description

Transplantable adenocarcinomas of the C3H mouse were treated with fractionated radiotherapy combined with local hyperthermia of 43.50C for 20 min before each dose fraction and local cure rate was determined. The sensitizing effect of hyperthermia was seen with fractionated treatment as well as with single treatment. The TER (thermal enhancement ratio), however, decreased with decreasing interval between the fractions. (orig.)

Abstract (German)

Transplantable Adenokarzinome der C3H-Maus wurden mit unterschiedlichen Strahlendosen in Kombination mit einer lokalen Tumorueberwaermung auf 43,50C fuer 20 min vor jeder Strahlendosis fraktioniert behandelt und die lokale Heilungsrate bestimmt. Der sensibilisierende Effekt der Hyperthermie trat wie bei Einzeitbehandlung auch bei fraktionierter Behandlung auf, nahm aber mit abnehmendem Fraktionierungsintervall ab. (orig.)

Additional details

Additional titles

Original title (German)
Fraktionierte Radio-Hyperthermie-Behandlung transplantabler Adenokarzinome der Maus

Publishing Information

Journal Title
Strahlentherapie
Journal Volume
154
Journal Issue
9
Series
Strahlentherapie.
Journal Page Range
653-655

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
10423358
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
CARCINOMAS; EXPERIMENTAL NEOPLASMS; FRACTIONATED IRRADIATION; HEALING; HEAT TREATMENTS; MICE; RADIOTHERAPY; TIME DEPENDENCE; TRANSPLANTS; X RADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL RECOVERY; DISEASES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MEDICINE; NEOPLASMS; RADIATIONS; RODENTS; THERAPY; VERTEBRATES