Published November 1998 | Version v1
Journal article Metadata-only

Experimental basis of cytokines application on acute radiation illness

Creators

  • 1. Gosudarstvenyj Nauchnyj Tsentr RF - Inst. Biofiziki, Filial N 1, Ozersk (Russian Federation)

Description

Comparative analysis of the available experimental data obtained with the use of laboratory animals (dogs, rats, mice and others) and concerning the perspective of preparations for hemopoiesis repair in case of radiation syndrome is performed. Efficiency of recombinant cytokines in the radiation syndrome treatment is shown as well as synergism of the cytokines effect in vivo and in vitro, conditions of the above preparations application for therapy

Abstract (Russian)

Проведен сравнительный анализ имеющихся в литературе экспериментальных данных, полученных на лабораторных животных (мышах, хомяках, морских свинках, собаках, крысах) и касающихся перспективности препаратов, направленных на восстановление гемопоэза при острой лучевой болезни. Показаны эффективность рекомбинантных цитокинов в лечении лучевой болезни, синергизм действия цитокинов in vivo и in vitro, условия терапевтического применения указанных средств

Additional details

Additional titles

Original title (Russian)
Экспериментальное обоснование применения цитокинов при острой лучевой болезни

Publishing Information

Journal Title
Radiatsionnaya Biologiya, Radioehkologiya
Journal Volume
38
Journal Issue
6
Journal Page Range
p. 854-873
ISSN
0869-8031
CODEN
RBIREJ

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
32022540
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ACUTE IRRADIATION; ANTITRUST REVIEW; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL REPAIR; BLOOD FORMATION; COMPARATIVE EVALUATIONS; DRUGS; IN VITRO; IN VIVO; LABORATORY ANIMALS; RADIATION SYNDROME; SYNERGISM; THERAPY
Descriptors DEC
ACUTE EXPOSURE; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; EVALUATION; IRRADIATION; LEGAL ASPECTS; MEDICINE; RADIATION EFFECTS; REPAIR

Optional Information

Notes
203 refs., 3 figs., 2 tabs.