Published November 2018 | Version v1
Journal article

Novel CT-Based Objective Imaging Biomarkers of Long-Term Radiation-Induced Lung Damage

  • 1. Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London (United Kingdom)
  • 2. Department of Oncology, University College London Hospital, London (United Kingdom)
  • 3. Department of Oncology, Guy's & St. Thomas' NHS Trust, London (United Kingdom)
  • 4. Department of Radiology, Royal Brompton Hospital, London (United Kingdom)
  • 5. Cancer Research UK and UCL Cancer Trials Centre, University College London, London (United Kingdom)

Description

Recent improvements in lung cancer survival have spurred an interest in understanding and minimizing long-term radiation-induced lung damage (RILD). However, there are still no objective criteria to quantify RILD, leading to variable reporting across centers and trials. We propose a set of objective imaging biomarkers for quantifying common radiologic findings observed 12 months after lung cancer radiation therapy.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.ijrobp.2018.06.006

Additional details

Identifiers

DOI
10.1016/j.ijrobp.2018.06.006;
PII
S0360301618309404;

Publishing Information

Journal Title
International Journal of Radiation Oncology, Biology and Physics
Journal Volume
102
Journal Issue
4
Journal Page Range
p. 1287-1298
ISSN
0360-3016
CODEN
IOBPD3

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
54107090
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BIOLOGICAL MARKERS; COMPUTERIZED TOMOGRAPHY; LUNGS; NEOPLASMS; RADIOTHERAPY
Descriptors DEC
BODY; DIAGNOSTIC TECHNIQUES; DISEASES; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY; TOMOGRAPHY

Optional Information

Copyright
Copyright (c) 2018 Elsevier Inc. All rights reserved.