Published 1982 | Version v1
Journal article Metadata-only

Light microscopical and histochemical findings on mouse lung following fast neutron and 60Co irradiation

Creators

  • 1. Forschungsinstitut fuer Lungenkrankheiten und Tuberkulose, Berlin-Buch (German Democratic Republic)
  • 2. Akademie der Wissenschaften der DDR, Berlin. Zentralinstitut fuer Molekularbiologie

Description

The morphological changes on the lungs of thorax-irradiated mice, receiving a single dose of fast neutrons and 60Co radiation, resp., were investigated. Lungs have been studied by histological and histochemical methods for 2 weeks up to 10 months. Changes were found after a time of 4-8 weeks. With histochemical methods more detailed damages were seen in contrast to routine histology. Two weeks post irradiation disturbances of phospholipid synthesis in alveolar epithel cells of type 2 were found. Radiation injuries of capillary endothelial cells are indicated by decreased ATPase damaged bronchial epithelium. (author)

Additional details

Additional titles

Original title (German)
Lichtmikroskopische und histochemische Befunde an der Maeuselunge nach Neutronen- und

Publishing Information

Journal Title
Z. Erkr. Atmungsorgane
Journal Volume
158
Journal Issue
3
Series
Z. Erkr. Atmungsorgane.
Journal Page Range
277-284
ISSN
0303-657X

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
14731763
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ATP-ASE; CATALYSIS; CHEST; COBALT 60; FAST NEUTRONS; GAMMA RADIATION; GLUCURONIDASE; LUNGS; METABOLISM; MICE; MORPHOLOGICAL CHANGES; PARTIAL BODY IRRADIATION; RADIATION INJURIES; RADIATION QUALITY
Descriptors DEC
ANIMALS; BARYONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; BODY AREAS; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; ELEMENTARY PARTICLES; ENZYMES; ESTERASES; EXTERNAL IRRADIATION; FERMIONS; GLYCOSYL HYDROLASES; HADRONS; HYDROLASES; INJURIES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NEUTRONS; NUCLEI; NUCLEONS; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; PHOSPHATASES; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RESPIRATORY SYSTEM; RODENTS; VERTEBRATES; YEARS LIVING RADIOISOTOPES