Diagnosis of bone infection by complementary role of technetium-99m MDP and technetium-99m hexamethylpropylene-amineoxime-leukocytes

Valuate complementary role of 99mTc-MDP bone scan and 99mTechnetium hexamethylpropylene-amineoxime (99mTc-HMPAO) labeled leukocyte scintigraphy in diagnosis of bone infection. Ninety one sites suspected to have bone infection were divided in to two groups: Group I 49 sites with current endo-prothesis; and group II 42 sites with no prosthesis. All patients were subjected to serial images of 99mTc-HMPAO labeled leukocyte (99mTc-white blood cells (WBCs)), triple phase bone scan (99mTc-MDP) and plain X-ray, in addition to clinical and bacteriological assessment, together with follow-up. Combined imaging with 99mTc-WBCs and 99mTc-MDP proved to be effective in early detection of bone infection in the presence or absence of prosthesis