Optimized adaptive reconstruction for quantification in PET-CT
Description
This study was initiated to evaluate an iterative reconstruction algorithm in positron emission tomography based on a regularization method to obtain convergence. Our aim was to assess its performance, in comparison with other currently available algorithms and to study the impact of the only parameter available to users for eventual optimization, both using anthropomorphic phantoms and clinical data. We confirm that this algorithm shows several advantages compared to the traditional OSEM-MLEM concerning noise, contrast and detectability. By using anthropomorphic phantoms and with access to more reconstruction parameters, the performance could be further improved to decrease the artefacts and the overestimation of certain metrics. Work in progress. (author)
Abstract (French)
L'etude a ete initiee a l'occasion de la disponibilite d'un algorithme iteratif de reconstruction en tomographie par emission de positons, qui presente l'avantage d'atteindre la convergence grace a une methode de regularisation. Il a donc fallu evaluer ses performances et son eventuel apport en comparaison aux algorithmes de reference, puis etudier l'influence du seul parametre accessible aux utilisateurs pour une optimisation en clinique. Pour cela, plusieurs tests ont ete realises, sur fantomes d'abord, puis sur patients car les resultats obtenus n'etaient pas directement transposables en clinique. Cet algorithme a de nombreux avantages par rapport au standard actuel OSEM-MLEM (moins de bruit, meilleur contraste, meilleure detectabilite des lesions) mais pourrait encore etre ameliore pour diminuer les artefacts et la surestimation de certaines metriques, grace a l'utilisation de fantomes plus anthropomorphiques et l'acces a plus de parametres de reconstruction. Des travaux sont encore en cours avec l'editeur. (auteur)
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Additional details
Additional titles
- Original title (French)
- Reconstruction adaptative optimisee pour la quantification en tomographie de positons couplee a un tomodensitometre
Publishing Information
- Imprint Pagination
- 134 p.
- Report number
- FRNC-TH--15810
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 55051175
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Thesis
- Descriptors DEI
- ALGORITHMS; CAT SCANNING; CONVERGENCE; FLUORINE 18; FLUORODEOXYGLUCOSE; IMAGE PROCESSING; ITERATIVE METHODS; PATIENTS; PHANTOMS; POSITRON COMPUTED TOMOGRAPHY
- Descriptors DEC
- ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CALCULATION METHODS; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; MATHEMATICAL LOGIC; MOCKUP; NANOSECONDS LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; PROCESSING; RADIOISOTOPES; STRUCTURAL MODELS; TOMOGRAPHY
Optional Information
- Notes
- 215 refs.; Available from the INIS Liaison Officer for France, see the INIS website for current contact and E-mail addresses