Interactions of the effects of hyperthermia and ionizing radiation on cell survival

It is shown that 1. hyperthermia increases the slope of the radiation survival curve and visa versa, 2. increasing hyperthermia doses result in increasing radiosensitization, 3. hyperthermia administered before radiation increases the extrapolation number of the radiation survival curve, 4. increasing temperature results in an increase in radiosensitization by hyperthermia, and 5. increasing temperature results in a decrease in thermal-sensitization by radiation. (author)