The engraftment dynamics evaluation of skin grafts via aluminium phthalocyanine nanoparticles using spectroscopic methods

The research and comparison of spectroscopic methods for assessment of skin grafts engraftment/rejection after the back cross skin transplantation of laboratory mice were carried out. The spectral analysis was performed via inflammatory reaction evaluation of the studied area. The inflammatory reaction intensity correlates with the fluorescence intensity of the aluminum phthalocyanine nanoparticles. The photodynamic therapy was carried out to improve the skin engraftment and reduce the inflammatory reaction. (paper)