Combined influence of nitrates and γ-radiation on proteinaseinhibitor and antioxidative blood plasma of rats

The separate and combine influence of nitrates (40 mg of sodium nitrate /100 g of body mass during 60 days) and γ-radiation (3 Gy) on condition of proteolytic and antioxidative blood plasma systems of rats have been investigated. There were increase of total proteolytic activity (TPA) on the 3-day, adaptive increase of α-antiproteinase inhibitor content (API) on the 7-day and the 14-day after factors separate action and tendency to increase TPA together with the invariable content of API after combine influence. The decrease of α-2-macroglobuline level on the 14-day after all influences and more significantly after combination of factors action have been also shown. The decrease of antioxidant system and system of free radicals inactivation have been observed. (author)