Lewy body dementia associated with anti-iglon 5 encephalitis detected on ¹⁸F fluorodeoxyglucose positron emission tomography/computed tomography and ^99mTC-trodat single-photon emission computed tomography/computed tomography

We present a case of Anti-IgLON 5 encephalitis with Lewy body dementia. ¹⁸F fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) scan and ^99mTc-TRODAT-1 SPECT/CT scan were done. ^99mTc-TRODAT-1 scan findings revealed severely reduced concentration of dopamine transporter in bilateral basal ganglia, suggestive of a degenerative parkinsonian disorder. ¹⁸F-FDG PET scan findings were suggestive of moderate-to-severe hypometabolism in the bilateral parieto-temporal and bilateral occipital cortices including the primary visual cortices, supporting Lewy body spectrum disease with associated hypermetabolism in the bilateral sensorimotor cortices, bilateral basal ganglia, thalami, brain stem, and bilateral cerebellar hemispheres suggestive of inflammatory pathology. (author)