Radiation-induced redox specification of sup(77)Br in aqueous solution as determined by anion chromatography

sup(77)Br is of potential use in diagnostic nuclear medicine as the parent of ultrashort-lived sup(77m)Se in a radioisotopic generator systems. The chemical forms(s) of the radiobromine in aqueous solution, and their radiation-induced chemical transformations, are of importance for biomedical generator development. Approximately 150 mCi of radiobromine, initially present as Brsup(-) was studied over a period of three weeks and analyzed for BrOsub(x)sup(-) (x=0-4) by anion exchange chromatography. Radiolysis of the solution gave rise to a small quantity of BrOsub(3)sup(-), but 99.5% of the activity remained as bromide. (author)