Published October 2012 | Version v1
Journal article

Ag-nanoparticle fractionation by low melting point agarose gel electrophoresis

  • 1. Consejo Superior de Investigaciones Cientificas (CSIC), Instituto de Ciencia y Tecnología de Polímeros (ICTP) (Spain)
  • 2. University of California, Santa Barbara, Department of Chemistry and Biochemistry (United States)

Description

The separation of surface-enhanced raman scattering (SERS)-active Ag-multi-nanoparticle (NP) assemblies by low melting point agarose gel electrophoresis was accomplished here by controlling surface charge using NP capping agents, and the pore size of agarose gel matrix. Detailed transmission electron microscopy analysis of excised gel fractions showed dimers and small clusters to have the greatest SERS activity and a mobility in between the monomers and large aggregates. This strategy enables one to: (1) stabilize small multispherical Ag clusters against further aggregation during purification; (2) fractionate and recover spherical assemblies by nuclearity; and (3) analyze SERS-enhancements for each fraction to optimize purification conditions.

Additional details

Identifiers

Publishing Information

Journal Title
Journal of Nanoparticle Research
Journal Volume
14
Journal Issue
10
Journal Page Range
p. 1-8
ISSN
1388-0764

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Copyright
Copyright (c) 2012 Springer Science+Business Media B.V.