Published April 1978
| Version v1
Journal article
Structure of psoralen-crosslinked ribosomal RNA from Drosophila melanogaster
Description
Ribosomal RNA from Drosophila melanogaster photoreacted with hydroxymethyltrioxsalen has been examined by electron microscopy. Reproducible patterns of hairpins were found in both the 26S and 18S RNA. The frequency of these hairpins and the amount of incorporated drug were dependent upon the conditions under which the crosslinking was performed. A prominent central hairpin occurs in the 26S RNA and the break that interrupts the continuity of the RNA chain is located within it. In addition to several small hairpins, the crosslinked 18S RNA contains a large open loop
Additional details
Identifiers
Publishing Information
- Journal Title
- Proceedings of the National Academy of Sciences
- Journal Volume
- 75
- Journal Issue
- 4
- Series
- Proc. Natl. Acad. Sci. U.S.A.
- Journal Page Range
- 1642-1646
- ISSN
- 0027-8424
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 9417501
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CHEMICAL RADIATION EFFECTS; CROSS-LINKING; DROSOPHILA; ELECTRON MICROSCOPY; IRRADIATION; MOLECULAR STRUCTURE; PSORALEN; RADIATION EFFECTS; RIBOSOMES; RNA; STRAND BREAKS; STRUCTURAL CHEMICAL ANALYSIS; ULTRAVIOLET RADIATION
- Descriptors DEC
- ANIMALS; ANTICOAGULANTS; ARTHROPODS; CELL CONSTITUENTS; CHEMICAL REACTIONS; DRUGS; ELECTROMAGNETIC RADIATION; FLIES; FRUIT FLIES; HETEROCYCLIC COMPOUNDS; INSECTS; INVERTEBRATES; MICROSCOPY; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; ORGANOIDS; POLYMERIZATION; RADIATIONS
Optional Information
- Notes
- Updated automatically by Metadata and Full-Text Enrichment Agent