Published March 1975
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Acute toxicity of ingested ruthenium-106
Creators
Description
The median lethal ingested dose of 106Ru for adult, weanling, and newborn rats was about 9, 20, and 2 mCi/kg, respectively. Death from gastrointestinal damage in dogs occurred at doses between 3.5 and 4.0 mCi/kg. Death was usually caused by severe damage to the lower bowel where the radiation dose was highest due to the prolonged residence time in that segment. Incorporation of 106Ru in the epithelium of the small intestine of the newborn contributed to the sensitivity of that age group. (U.S.)
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Additional details
Additional titles
- Augmented title (English)
- Rats, dogs
Publishing Information
- Imprint Title
- Pacific Northwest Laboratory annual report for 1974 to the ERDA Division of Biomedical and Environmental Research. Part I. Biomedical sciences
- Imprint Pagination
- p. 111-114.
- Report number
- BNWL--1950(Pt.1)
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 6209749
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Progress Report
- Descriptors DEI
- AGE DEPENDENCE; BIOLOGICAL RADIATION EFFECTS; DEATH; DOGS; GASTROINTESTINAL TRACT; INGESTION; LETHAL RADIATION DOSE; RADIONUCLIDE KINETICS; RATS; RUTHENIUM 106; TOXICITY
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; DIGESTIVE SYSTEM; EVEN-EVEN NUCLEI; INTAKE; INTERMEDIATE MASS NUCLEI; ISOTOPES; KINETICS; MAMMALS; NUCLEI; RADIATION DOSES; RADIATION EFFECTS; RADIOISOTOPES; RODENTS; RUTHENIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES