Published 2011 | Version v1
Journal article

Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives

  • 1. Advinus Therapeutics Pvt. Ltd., Bangalore (India)
  • 2. Advinus Therapeutics Pvt. Ltd., Bangalore (India). Dept. of Studies in Industrial Chemistry
  • 3. Advinus Therapeutics Pvt. Ltd., Bangalore (India). Dept. of Studies in Chemistry
  • 4. Kuvempu University, Jnana Sahyadri, Karnataka (India). Dept. of Biochemistry
  • 5. Kuvempu University, Jnana Sahyadri, Karnataka (India). Dept. of Plant Pathology

Description

A series of some new 3-isoxazoline substituted methyl-3-methoxy-2-(4-oxo-3,4- dihydrophthalazine-1-yl)prop-2-enoate derivatives were designed and synthesized from methyl- (4-oxo-3,4-dihydrophthalazine-1-yl)acetate, which in turn was prepared from phthalic anhydride. The structures of synthesized new compounds were characterized by spectral data and studied for their antimicrobial activities and cytotoxicity. Several of these compounds showed good antimicrobial activity (author)

Availability note (English)

Available from http://www.scielo.br/pdf/jbchs/v22n5/v22n5a06.pdf

Additional details

Publishing Information

Journal Title
Journal of the Brazilian Chemical Society
Journal Volume
22
Journal Issue
5
Journal Page Range
p. 849-856
ISSN
0103-5053
CODEN
JOCSET