The activity and localization of DNAases in the liver and spleen of animals followed up during acute radiation sickness and after treatment with the transplanted bone marrow

The effect of bone marrow transplantation on the activity and localization of acidic and neutral DNAases in the liver and spleen of irradiated rats has been investigated. X-irradiation of animals with doses of 800-850 R makes the enzymes under study leave the sites they are usually localized at, and drastically increases their activity, which is particularly pronounced in the case of the acidic DNAase studies. The activity of DNAases decreases under the effect of the transplanted bone marrow and the localization of the enzymes is almost the same as in the intact animals