Published September 1989 | Version v1
Journal article Metadata-only

UV-induced formation of DNA-protein cross-links in chromatin in the presence of chemical agents

Creators

  • 1. AN SSSR, Moscow (USSR). Inst. Khimicheskoj Fiziki

Description

Hindered phenols, quinones, and SH-compounds have been studied as possible protectors and sensibilizers of DNA-protein cross-linking in chromatin. Efficacy of cross-linking was estimated by the quantity of protein linked to DNA after UV-irradiation at 254 nm in the presence of chemical agents. Phenols an quinones exert protective influence on cross-linking whereas DNA- protein cross-links are sensibilized by cysteine hydrochloride

Additional details

Additional titles

Original title (Russian)
UF-индуцированное образование сшивок DNK-белок в хроматине в присуцтвии химических агентов

Publishing Information

Journal Title
Izvestiya Akademii Nauk SSSR, Seriya Biologicheskaya
Journal Issue
no.5
Series
Izv. Akad. Nauk SSSR, Ser. Biol.
ISSN
0002-3329
CODEN
IANBA

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
21018723
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CROSS-LINKING; DNA; DOSE-RESPONSE RELATIONSHIPS; NUCLEOTIDES; PROTEINS; ULTRAVIOLET RADIATION
Descriptors DEC
BIOLOGICAL EFFECTS; CHEMICAL REACTIONS; ELECTROMAGNETIC RADIATION; NUCLEIC ACIDS; ORGANIC COMPOUNDS; POLYMERIZATION; RADIATION EFFECTS; RADIATIONS