Published March 2005 | Version v1
Journal article Metadata-only

Feasibility study on a noninvasive measurement system for boron concentration

Creators

  • 1. Tokyo Univ., Tokyo (Japan). Research Center for Nuclear Science and Technology
  • 2. National Inst. of Radiological Sciences, Chiba (Japan)
  • 3. Hiroshima Univ., Hiroshima (Japan). Research Inst. for Radiation Biology and Medicine

Description

The kinematics of boron compounds in vivo is crucial to fully and safely utilize boron neutron capture therapy. In this paper, we proposed a prompt gamma-ray Compton scatter camera (PG-CSC), which can evaluate the 3-D kinematics of boron compounds without invasion. This PG-CSC combines a Compton camera with prompt gamma-ray analysis. The results of its design optimization and tests using simulations showed that one-hour-measurement was sufficient to evaluate a 3-D boron concentration distribution in a rat's brain with the resolution of 1 mm in full width half maximum (FWHM). (author)

Additional details

Publishing Information

Journal Title
Igaku Butsuri
Journal Volume
25
Journal Issue
1
Journal Page Range
p. 3-12
ISSN
1345-5354

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
36099948
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BGO DETECTORS; BORON COMPOUNDS; BRAIN; COMPTON EFFECT; IMAGE PROCESSING; RATS; SI SEMICONDUCTOR DETECTORS; SIMULATION; SPATIAL RESOLUTION; THERMAL NEUTRONS; THREE-DIMENSIONAL CALCULATIONS; TISSUE DISTRIBUTION
Descriptors DEC
ANIMALS; BARYONS; BASIC INTERACTIONS; BODY; CENTRAL NERVOUS SYSTEM; DISTRIBUTION; ELASTIC SCATTERING; ELECTROMAGNETIC INTERACTIONS; ELEMENTARY PARTICLES; FERMIONS; HADRONS; INTERACTIONS; MAMMALS; MEASURING INSTRUMENTS; NERVOUS SYSTEM; NEUTRONS; NUCLEONS; ORGANS; PROCESSING; RADIATION DETECTORS; RESOLUTION; RODENTS; SCATTERING; SCINTILLATION COUNTERS; SEMICONDUCTOR DETECTORS; SOLID SCINTILLATION DETECTORS; VERTEBRATES