Published October 2006
| Version v1
Journal article
Assessing the 210At impurity in the production of 211At for radiotherapy by 210Po analysis via isotope dilution alpha spectrometry
Creators
- 1. National Institute of Standards and Technology, Radioactivity Group, 100 Bureau Drive MS8462, Gaithersburg, MD 21702 (United States)
- 2. National Institutes of Health, Cyclotron Facilities, 10 Center Drive, Bethesda, MD (United States)
- 3. International Atomic Energy Agency, Dosimetry and Radiation Physics Section, Wagramer Strasse 5, P.O. Box 100, A-1400 Vienna (Austria)
Description
A method for assessing the impurity 210At in cyclotron-produced 211At via isotope dilution alpha spectrometry is presented. The activity of 210At is quantified by measuring the activity of daughter nuclide 210Po. Counting sources are prepared by spontaneous deposition of Po on a silver disc. Activity of 210At (at the time of 210Po maximum activity) is found to be 83.5+/-9.0Bq, corresponding to an atom ratio (210At:211At at the time of distillation) of 0.010+/-0.007% (k=2). The method produces high-quality alpha spectra, with baseline alpha-peak resolution and chemical yields of greater than 85%
Additional details
Identifiers
- DOI
- 10.1016/j.apradiso.2006.02.046;
- PII
- S0969-8043(06)00100-X;
Publishing Information
- Journal Title
- Applied Radiation and Isotopes
- Journal Volume
- 64
- Journal Issue
- 10-11
- Journal Page Range
- p. 1365-1369
- ISSN
- 0969-8043
- CODEN
- ARISEF
Conference
- Title
- 15. international conference on radionuclide metrology and its applications
- Acronym
- ICRM 2005
- Dates
- 5-9 Sep 2005
- Place
- Oxford (United Kingdom)
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 38025333
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ALPHA SPECTRA; ALPHA SPECTROSCOPY; ASTATINE 210; ASTATINE 211; CYCLOTRONS; IMPURITIES; ISOTOPE DILUTION; PEAKS; POLONIUM 210; RADIOTHERAPY
- Descriptors DEC
- ACCELERATORS; ALPHA DECAY RADIOISOTOPES; ASTATINE ISOTOPES; BETA DECAY RADIOISOTOPES; CYCLIC ACCELERATORS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MEDICINE; NANOSECONDS LIVING RADIOISOTOPES; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; POLONIUM ISOTOPES; RADIOISOTOPES; RADIOLOGY; SPECTRA; SPECTROSCOPY; THERAPY; TRACER TECHNIQUES
Optional Information
- Copyright
- Copyright (c) 2006 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.