Preliminary evaluation of 4 rings/7 slices domestic PET scanner

PURPOSE: To test the preliminary clinical performance of 4 rings/7 slices, AFOV 8 cm PET scanner made in China. METHODS: Based on phantom test and animal study, PET imaging were performed on a normal volunteer and 7 patients 1.5 hours after intravenous injection of 370 MBq of 18F-FDG. The acquisition time of whole body imaging for adult was 1.5 hours (11 bed position), whereas myocardium and brain imaging was 0.5 hours (2∼3 bed position). RESULTS: Φ1∼3 cm positive and negative foci could be displayed in phantom. 8 cases of coronal and sagittal whole body tomographic images were clearly demonstrated. Brain, myocardium and bladder were significantly displayed in normal volunteer with normal food and drink. 6 malignant lesions of 2 patients concentrated 18F-FDG significantly and 2 benign lesions of 2 patients did not concentrated it. Recurrence and metastasis were excluded in 2 patients with carcinoma after operation and chemotherapy. Whether normal myocardium display or not were dependent on glucose loading. 18F-FDG myocardium images matched well with 99mTc-MIBI myocardial perfusion images in a patient with remote myocardial infarction. Cerebral cortex images well visualized in all subjects. CONCLUSIONS: The performance of this PET scanner showed that it reached the level of middle stage of 8th decade's 4 rings/7 slices PET and possessed the coronal and sagittal whole body tomographic function of 9th decade's PET. It can be used in whole body tumor imaging, myocardial viability evaluation and preoperation localization of functional epileptic foci, but operating and software function should be improved