Development of new filler materials using a radiation cross-linking reaction

1. Qualification of radiation cross-linked poly glutamic acid (γ-PGA) for developing new filler - Optimization of viscoelasticity of γ-PGA filler by radiation cross-linking with different type, molecular weight, concentration of γ-PGA, and irradiation dose 2. Evaluation of toxicological safety and license reference test - Confirmation of toxicological safety of radiation cross-linked γ-PGA using WST assay with 3T3-L1 cell line 3. Development of mass produce strain for γ-PGA - Isolation of γ-PGA producing Bacillus spp. from soil and development of radiation induced mutant, which was deposited and applied a patent