Published October 1986 | Version v1
Journal article Metadata-only

153Sm-EDTMP, a potential therapeutic bone agent

Creators

  • 1. Dow Chemical Co., Freeport, TX (USA)
  • 2. Harry S. Truman Memorial Veterans Hospital, Columbia, MO (USA)
  • 3. Missouri Univ., Columbia (USA). Dept. of Radiology
  • 4. Missouri Univ., Columbia (USA). Dept. of Chemistry

Description

Ethylenediaminetetramethylenephosphonic acid (EDTMP) forms a stable complex with Sm-153. Biodistributions in rats and rabbits show the complex to be an excellent bone agent. The nuclear properties of Sm-153 make it an ideal candidate for therapy. This paper discusses pre-clinical development of Sm-153-EDTMP as a therapeutic bone agent. (author)

Additional details

Publishing Information

Journal Title
J. Labelled Compd. Radiopharm.
Journal Volume
23
Journal Issue
10-12
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
1344-1346
ISSN
0362-4803
CODEN
JLCRD

Conference

Title
6. international symposium on radiopharmaceutical chemistry.
Dates
29 Jun - 3 Jul 1986.
Place
Boston, MA (USA).

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
18082398
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
LIGANDS; ORGANIC PHOSPHORUS COMPOUNDS; RABBITS; RADIOPHARMACEUTICALS; RATS; SAMARIUM 153; SKELETON
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; DRUGS; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MATERIALS; NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RARE EARTH NUCLEI; RODENTS; SAMARIUM ISOTOPES; VERTEBRATES