Importance of the sequence of application of ultrasound and ionizing radiation for survival of yeast cells

The authors submit the results of experiments involving combined treatment of yeast cells, of different genotypes, with ultrasound and ionizing radiation. γ-Radiation was delivered either before or after ultrasound. It was shown that the extent of the synergistic effect of the two factors depends on the sequence of the delivery thereof: it was larger with a combination ''γ-radiation+ultrasound''. The combined effect was less pronounced for the rad 51 mutation which is radiosensitive and incapable of postradiation repair