Published April 2010 | Version v1
Journal article Metadata-only

Influence of catechins on bystander responses in CHO cells induced by alpha-particle irradiation

Creators

  • 1. Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong)

Description

In this work, we studied alpha-particle induced and medium-mediated bystander effects in Chinese hamster ovary (CHO) cells through micronucleus (MN) assay. We showed that signal transduction from irradiated cells to bystander cells occur within a short time after irradiation. We then studied the effects of ROS (reactive oxygen species)-scavenging catechins in the medium before irradiation. We observed decreases in the percentage of bystander cells with MN formation and thus proved the protection effect of catechins on bystander cells from radiation.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.apradiso.2009.10.028

Additional details

Identifiers

DOI
10.1016/j.apradiso.2009.10.028;
PII
S0969-8043(09)00645-9;

Publishing Information

Journal Title
Applied Radiation and Isotopes
Journal Volume
68
Journal Issue
4-5
Journal Page Range
p. 726-729
ISSN
0969-8043
CODEN
ARISEF

Conference

Title
7. international topical meeting on industrial radiation and radio isotope measurement application
Acronym
IRRMA-7
Dates
22-27 Jun 2008
Place
Prague (Czech Republic)

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
41068553
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ALPHA PARTICLES; BIOLOGICAL RADIATION EFFECTS; CHO CELLS; HAMSTERS; IRRADIATION; OVARIES; POLYPHENOLS; SCAVENGING
Descriptors DEC
ANIMAL CELLS; ANIMALS; AROMATICS; BIOLOGICAL EFFECTS; BODY; CHARGED PARTICLES; FEMALE GENITALS; GONADS; HYDROXY COMPOUNDS; IONIZING RADIATIONS; MAMMALS; ORGANIC COMPOUNDS; ORGANS; PHENOLS; RADIATION EFFECTS; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES

Optional Information

Copyright
Copyright (c) 2009 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.