Published July 1976
| Version v1
Journal article
Role of bacterial and phage recombination systems and of DNA replication in genetic recombination of UV-irradiated phage lambda
Creators
- 1. Instituto de Investigaciones Citologicas, Valencia (Spain). Lab. de Genetica Microbiana
Description
A study was made in E. coli K12 of the influence of the bacterial Rec and phage lambda Red recombination systems on the rescue of the 0+ gene from the prophage by a superinfecting 0- phage, UV irradiated or not. In the absence of UV irradiation the Red system produces more recombinants than does the Rec system, and its action requires DNA replication. The presence of UV lesions in the lambda DNA facilitates the action of the Rec system, which is more efficient in this instance than the Red system and can act in the absence of DNA replication. In all cases, there is a cooperation between the two generalized recombination systems. (orig.)
Abstract (German)
In E. coli K12 wurde der Einfluβ des bakteriellen Rec-Rekombinationssystems und des Red-Systems des lambda-Phagen auf die Erhaltung des 0+-Gens des Prophagen durch einen superinfizioesen 0--Phagen untersucht, der entweder bestrahlt war oder nicht. In Abwesenheit von UV-Bestrahlung produziert das Red-System mehr Rekombination als das Rec-System und seine Funktion erfordert eine DNS-Replikation. Die Anwesenheit von UV-Schaeden in der lambda-DNS erleichtert die Funktion des Rec-Systems, die dann wirksamer ist als das Red-System und auch ohne DNS-Replikation funktioniert. In allen Faellen findet eine Kooperation beider generalisierter Rekombinationssysteme statt. (orig.)Additional details
Identifiers
- DOI
- 10.1007/bf00267982;
Publishing Information
- Journal Title
- Molecular and General Genetics MGG
- Journal Volume
- 146
- Journal Issue
- 1
- Series
- Mol. Gen. Genet.
- Journal Page Range
- 51-54
- ISSN
- 0026-8925
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 7270599
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BACTERIOPHAGES; BIOLOGICAL RADIATION EFFECTS; DNA REPLICATION; ESCHERICHIA COLI; GENE RECOMBINATION; IRRADIATION; MOLECULAR BIOLOGY; RADIATION INJURIES; ULTRAVIOLET RADIATION
- Descriptors DEC
- BACTERIA; BIOLOGICAL EFFECTS; DISEASES; ELECTROMAGNETIC RADIATION; INJURIES; MICROORGANISMS; NUCLEIC ACID REPLICATION; PARASITES; RADIATION EFFECTS; RADIATIONS; VIRUSES
Optional Information
- Notes
- 1 fig.; 2 tabs.; 22 refs.; Updated automatically by Metadata and Full-Text Enrichment Agent