Published January 2016
| Version v1
Journal article
Nuclear factor-kappa beta/P53 mediated signaling pathways assisted the recovery of radiation induced gastrointestinal injuries in mice by prophylactic administration of a combination of podophyllotoxin and Rutin
- 1. Division of Radioprotective Drug Development Research, Institute of Nuclear Medicine and Allied Sciences, Delhi (India)
Description
Exposure to high doses of ionising radiation leads to the loss of regenerative potential of intestinal crypts and mucosal inflammation. The current study has been envisaged to explore the potential of a combination of podophyllotoxin and rutin (G-003M) in reducing radiation induced damage in mice gastro intestine (GI). C57/BL6 mice were exposed to lethal dose (9Gy) of γ-radiation
Additional details
Publishing Information
- Journal Title
- Journal of Radiation and Cancer Research
- Journal Volume
- 7
- Journal Issue
- 1
- Journal Page Range
- p. 45
- ISSN
- 0973-0168
Conference
- Title
- international conference on radiation research - impact on human health and environment and first biennial meeting of society for radiation research: abstracts
- Acronym
- ICRR-HHE 2016
- Dates
- 11-13 Oct 2016
- Place
- Mumbai (India)
INIS
- Country of Publication
- India
- Country of Input or Organization
- India
- INIS RN
- 47104314
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CELL FLOW SYSTEMS; INFLAMMATION; INTESTINES; LETHAL RADIATION DOSE; MICE; RADIATION DOSES; RADIOPROTECTIVE SUBSTANCES
- Descriptors DEC
- ANIMALS; BODY; DIGESTIVE SYSTEM; DOSES; DRUGS; GASTROINTESTINAL TRACT; LETHAL DOSES; MAMMALS; ORGANS; PATHOLOGICAL CHANGES; RADIATION DOSES; RESPONSE MODIFYING FACTORS; RODENTS; SYMPTOMS; VERTEBRATES