Published May 1989 | Version v1
Journal article

Studies on derivatives of bat chelates labelled with 67Ga, 113mIn and 201Ti: Pt. 2

  • 1. Beijing Normal Univ., BJ (China). Dept. of Chemistry

Description

The net charges of the new potential myocardial imaging chelates M-BAT-TE and M-BAT-HM (M =Ca3+, In3+, Tl3+) were determined by means of the ion exchange resin method. The net charges of these six chelates were all identified as + 1. In determining stability constants the pH electric potential method was used. The experimental results show that the magnitudes of the stability constants are in such an order: Tl-HM>In-HM>Ca-HM; Tl-TE>Ga-TE. This order is identical to the order of the heart uptake in mice of these chelates

Additional details

Additional titles

Subtitle (English)
Determination of net charges and stability constants of bat chelates

Publishing Information

Journal Title
Journal of Isotopes
Journal Volume
2
Journal Issue
2
Series
J. Isot.
Journal Page Range
98-102
ISSN
1000-7512