Adaptation of a May spinning top monodispersed aerosol generator to animal inhalation studies
Creators
Description
Studies of respiratory deposition of aerosols in the beagle dog will be undertaken using monodispersed aerosols of 198Au tagged iron oxide or metallic gold. In preparation for this study a dog exposure glove box was modified to accommodate a May spinning top aerosol generator. This generator is capable of generating monodispersed aerosols in the size range of 0.5 μm to 5 μm aerodynamic equivalent diameter, a range useful for such a study. Preliminary operation checks of the aerosol system have begun using uranine dye aerosols in place of the 198Au tagged aerosols. A mass concentration 2.9 mg/m3 of 2 μm AED particles has been obtained. Such a concentration will be sufficient for tagged aerosols to be used in the study. (U.S.)
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Additional details
Additional titles
- Augmented title (English)
- "1"9"8Au
Publishing Information
- Imprint Title
- Pacific Northwest Laboratory annual report for 1974 to the ERDA Division of Biomedical and Environmental Research. Part I. Biomedical sciences
- Imprint Pagination
- 63 p.
- Report number
- BNWL--1950(Pt.1)
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 6209674
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S46: INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY;
- Resource subtype / Literary indicator
- Progress Report
- Descriptors DEI
- AEROSOL GENERATORS; AEROSOLS; BEAGLES; DEPOSITION; GLOVEBOXES; GOLD; GOLD 198; INHALATION; IRON OXIDES; RESPIRATORY SYSTEM; SPECIFICATIONS
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CHALCOGENIDES; COLLOIDS; DAYS LIVING RADIOISOTOPES; DISPERSIONS; DOGS; ELEMENTS; GOLD ISOTOPES; HEAVY NUCLEI; INTAKE; IRON COMPOUNDS; ISOTOPES; LABORATORY EQUIPMENT; MAMMALS; METALS; NUCLEI; ODD-ODD NUCLEI; OXIDES; OXYGEN COMPOUNDS; RADIOISOTOPES; SOLS; TRANSITION ELEMENT COMPOUNDS; TRANSITION ELEMENTS; VERTEBRATES