The energetic state of rat's small intestine mitochondria under exposure to X-ray ionizing radiation with low intensity

Influence of low-intensity ionizing radiation with single dose (0.055 Gy x min-1) in doses of 0.1, 0.5, and 1.0 Gy on a metabolic state of the respiratory chain of rat's small intestine mitochondria is investigated. The damage of relations of the oxidative phosphorylation processes in mitochondria, which is expressed in the uncoupling of the processes of respiration and phosphorylation and in a decline of the phosphorylation rate and the activity of ATP-hydrolase reactions, is established. These changes are observed at all time of research and intensified with a growth of the radiation absorbed dose.