Determination of the survival curve of the cell irradiated with low dose rate neutrons
Creators
- 1. Minas Gerais Univ., Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear
- 2. Fundacao Ezequiel Dias, Belo Horizonte, MG (Brazil). Dept. de Pesquisa. Lab. de Bioquimica
Description
The effect of the radiation in tissue and cells are a theme of extreme importance and that is receiving large attention more and more now. This work purposes to evaluate the deleterious effects of the neutrons radiation at low dose rate in lineages of human cancerous cells through the analysis of survival curves. Deleterious effects due to radiation of low dose rate (3.8 mSv/hr) were observed in cells of the lineage HeLa S3. Previous studies, in lineage HN5 of tongue carcinoma, showed survive level to 0.2Sv of 80%, compatible to the value of 88,57% 0.4 Sv obtained for HeLa S3. In a close future, with the molecular biology characterization of a great number or possibly all cancer types (that will be accelerated largely with the conclusion of the human genome project), studies like this, can be much more specific, and could determine the efficiency of the neutrons or any other radiation type for each one of those types. Those data would have of great value for the medicine and they would help to plan the treatments better. (author)
Additional details
Additional titles
- Original title (Portuguese)
- Determinacao da curva de sobrevivencia de celulas irradiadas com neutrons a baixa taxa de dose
Publishing Information
- Imprint Title
- Nuclear future: thinking for building. Proceedings of the 5. Brazilian national meeting on nuclear applications; 8. General congress on nuclear energy; 12. Brazilian national meeting on reactor physics and thermal hydraulics
- Imprint Pagination
- [1450 p.]
- Journal Page Range
- [5 p.]
Conference
- Title
- 5. Brazilian national meeting on nuclear applications; 8. General congress on nuclear energy; 12. Brazilian national meeting on reactor physics and thermal hydraulics
- Original Conference Title
- 5. Encontro nacional de aplicacoes nucleares
- Dates
- 15-20 Oct 2000
- Place
- Rio de Janeiro, RJ (Brazil)
INIS
- Country of Publication
- Brazil
- Country of Input or Organization
- Brazil
- INIS RN
- 33064852
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference, Numerical Data
- Descriptors DEI
- BIOLOGICAL EFFECTS; EXPERIMENTAL DATA; IRRADIATION; LOW DOSE IRRADIATION; NEUTRON THERAPY; RADIOSENSITIVITY; SURVIVAL CURVES; TUMOR CELLS
- Descriptors DEC
- ANIMAL CELLS; DATA; INFORMATION; IRRADIATION; MEDICINE; NUCLEAR MEDICINE; NUMERICAL DATA; RADIOLOGY; RADIOTHERAPY; THERAPY
Optional Information
- Notes
- 6 refs., 3 figs., 2 tabs., 2 graphs Imprint:Published only in CD-Rom;Futuro nuclear: refletindo para construir. Anais do 5. Encontro nacional de aplicacoes nucleares; 8. Congresso geral de energia nuclear; 12. Encontro nacional de fisica de reatores e termo-hidraulica