Published May 1976 | Version v1
Journal article

Effect of long-wave ultraviolet light on the lens. I. Model systems for detecting and measuring effect on the lens in vitro

  • 1. Emory Univ., Atlanta

Description

Rat, mouse, and chick lenses incubated with 3-aminotriazole under long-wave ultraviolet (UV) show reduced accumulation and incorporation of leucine and a loss of glutathione. The effect on leucine incorporation is strikingly enhanced when capsule-epithelium pools are incubated. The procedure may identify photosensitizers or metabolic inhibitors which are cataractogenic when acting in conjunction with UV

Additional details

Publishing Information

Journal Title
Invest. Ophthalmol.
Journal Volume
15
Journal Issue
5
Series
Invest. Ophthalmol.
Journal Page Range
405-407