Role of radiopharmaceuticals in nuclear hematology

The continued reassessment and refinement of techniques during the past few decades have generated a series of radioactive agents that have been evaluated as tracers for cellular blood elements. A few of the radiopharmaceuticals which have contributed a great deal to nuclear hematology have been concluded in detail. The mode of their actions, merits and disadvantages have been discussed. None of te compounds currently available appear to meet all the ideal requirements in that it is still impossible to selectively label and follow a cohort of cells for their entire life span with external monitoring by currently available instrumentation. Nevertheless, the newer agents show great promise as potential radiopharmaceuticals designed to investigate a variety of hematologic disease in humans