Published April 2002 | Version v1
Journal article Metadata-only

The application of 99Tcm-MIBI scintimammography to diagnose multidrug resistance of breast cancer

Creators

  • 1. Zhengzhou Univ., Zhengzhou (China). Dept. of Nuclear Medicine, The First Affiliated Hospital

Description

The author discussed the main mechanism of multidrug resistance of breast cancer tissues, and the correlation between technetium-99m sestamibi (99Tcm-MIBI) breast imaging results, with the expression of drug resistance proteins P-glycoprotein and glutathione-S-transferase-π in human breast cancer. Through not all the results reported before matched each other, as a kind of a noninvasive simple functional test imaging technology in vitro, SPECT can be used to diagnose P-glycoprotein expression in breast cancer, and can be used to predict chemotherapy response

Additional details

Publishing Information

Journal Title
Foreign Medical Sciences. Section of Radiation Medicine and Nuclear Medicine
Journal Volume
26
Journal Issue
2
Journal Page Range
p. 67-71
ISSN
1001-098X

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
33065004
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
CARCINOMAS; DIAGNOSIS; DRUGS; GLUTATHIONE; GLYCOPROTEINS; ISONITRILES; MAMMARY GLANDS; PHARMACOLOGY; RADIOPHARMACEUTICALS; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TECHNETIUM 99; TRANSFERASES
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; CARBONIC ACID DERIVATIVES; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; ENZYMES; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; PEPTIDES; POLYPEPTIDES; PROTEINS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; SACCHARIDES; TECHNETIUM ISOTOPES; TOMOGRAPHY; YEARS LIVING RADIOISOTOPES