Published March 1994
| Version v1
Journal article
The preparation of 125I-labelled sodium polystyrene sulphonate
Creators
- 1. British Geological Survey, Keyworth (United Kingdom). Fluid Processes Research Group
Description
The anionic polymer, sodium polystyrene p-sulphonate (PSSNa), was labelled with iodine-125. Standard radio-iodination for proteins proceeds via phenol groups. As PSSNa contains no phenolic functions these were introduced by reaction with sodium hydroxide. The optimized conditions gave barely discernible phenolic incorporation so the properties of the bulk PSSNa were not noticeably altered. The modified PSSNA was then radio-iodinated by the standard technique. The yield, activity and stability of the product were determined by size exclusion chromatography. (Author)
Additional details
Publishing Information
- Journal Title
- Applied Radiation and Isotopes
- Journal Volume
- 45
- Journal Issue
- 3
- Journal Page Range
- p. 345-351.
- ISSN
- 0969-8043
- CODEN
- ARISEF
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 25033226
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- CHEMICAL PREPARATION; CHEMICAL REACTION YIELD; IODINE 125; LABELLING; OPTIMIZATION; POLYSTYRENE; RADIOPHARMACEUTICALS; SULFONATES
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IODINE ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC POLYMERS; ORGANIC SULFUR COMPOUNDS; POLYMERS; POLYOLEFINS; POLYVINYLS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SYNTHESIS; YIELDS