Published July 19, 1988 | Version v1
Journal article Metadata-only

Demonstration of β-adrenergic receptors in rat nasal glands by an in vitro autoradiographic technique

Creators

  • 1. Katholieke Univ., Nijmegen, Dept. of Otorhinaryngology (Netherlands)
  • 2. Katholieke Univ., Nijmegen, Dept. of Pharmacology (Netherlands)

Description

The distribution of β-adrenergic receptors in rat nasal glands has been investigated with the use of an in vitro autoradiographic technique. Radioligand binding studies indicated that [125I]cyanopindol binds specifically to β-adrenergic receptors in cryostat sections of these glands. Autoradiograms generated after incubation with 0.02nM [125I]cyanopindol and dipping in nuclear K2 emulsion, showed specific labelling of the striated excretory ducts. These in vitor observations suggest a sympathetic control of the ion and water content of the glandular secretion

Additional details

Publishing Information

Journal Title
Neuroscience Letters
Journal Volume
90
Journal Issue
1,2
Series
Neurosci. Lett.
Journal Page Range
75-77
ISSN
0304-3940
CODEN
NELED

INIS

Country of Publication
Ireland
Country of Input or Organization
Ireland
INIS RN
20018541
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
AUTORADIOGRAPHY; GLANDS; IN VITRO; LABELLED COMPOUNDS; LIGANDS; NERVOUS SYSTEM; NOSE; RATS; RECEPTORS; SECRETION; WATER
Descriptors DEC
ANIMALS; BODY; BODY AREAS; FACE; HEAD; HYDROGEN COMPOUNDS; MAMMALS; ORGANS; OXYGEN COMPOUNDS; POLAR SOLVENTS; RESPIRATORY SYSTEM; RODENTS; SOLVENTS; VERTEBRATES