Published 1979 | Version v1
Report Metadata-only

DNA repair in Haemophilus influenzae

Creators

Description

A mutant (hex-) of Haemophilus influenzae which does not discriminate between low efficiency (LE) and high efficiency (HE) markers has been isolated. The mutant is like wild type in its sensitivity to ultraviolet (UV) radiation, methyl methane sulfonate (MMS), mitomycin C (MC) and nitrous acid (NA). As compared to the wild type, the mutant shows much higher spontaneous as well as bromouracil (BrU)-induced mutation frequencies. Biological inactivation of transforming DNA that had been UV-irradiated or treated with MMS has been studied on the widely used wild type Haemophilus influenzae Rd and several repair deficient mutant strains

Availability note (English)

University Microfilms Order No. 80-06,222.

Additional details

Publishing Information

Imprint Pagination
157 p.

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
13668542
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Thesis, Non-conventional Literature
Descriptors DEI
BIOCHEMISTRY; BIOLOGICAL PATHWAYS; BIOLOGICAL REPAIR; DNA; ENZYME INHIBITORS; HAEMOPHILUS; METABOLISM; MMS; MUTAGENESIS; MUTATION FREQUENCY; MUTATIONS; RADIATION EFFECTS; RADIOSENSITIVITY; RESPONSE MODIFYING FACTORS; ULTRAVIOLET RADIATION
Descriptors DEC
BACTERIA; BIOLOGICAL RECOVERY; CHEMISTRY; ELECTROMAGNETIC RADIATION; ESTERS; MICROORGANISMS; MUTAGENS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; RADIATIONS; SULFONIC ACID ESTERS