Published May 1981
| Version v1
Journal article
Preparation of tritiated 2, 4-diamino-5-adamantyl-6-methylpyrimidine
Creators
- 1. Roswell Park Memorial Inst., Buffalo, NY (USA). Dept. of Experimental Therapeutics
- 2. Radiochemical Centre Ltd., Amersham (UK)
Description
Tritium labeled 2,4-diamino-5-adamantyl-6-methylpyrimidine was prepared by a platinum metal catalyzed tritium exchange for 4 hr at 700. The crude material was purified on a Sephadex G-25 column and converted to its water soluble ethanesulfonate salt. The analysis of the purified material revealed that 43% of the tritium was located in the 6-methyl group and the remainder in the adamantane moiety of the molecule. (author)
Additional details
Publishing Information
- Journal Title
- J. Labelled Compd. Radiopharm.
- Journal Volume
- 18
- Journal Issue
- 5
- Series
- J. Labelled Compd. Radiopharm.
- Journal Page Range
- 683-693
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 12618158
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- AMINES; ANTINEOPLASTIC DRUGS; CATALYSIS; CHEMICAL PREPARATION; ISOTOPIC EXCHANGE; METHYL RADICALS; PYRIMIDINES; RADIOPHARMACEUTICALS; TRITIUM; TRITIUM COMPOUNDS
- Descriptors DEC
- ALKYL RADICALS; AZINES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DRUGS; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; HYDROGEN ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADICALS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SYNTHESIS; YEARS LIVING RADIOISOTOPES