Published January 2002 | Version v1
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Biodistribution of the 18F-labelled advanced glycation end products Nε-carboxymethyllysine (CML) and Nε-carboxyethyllysine (CEL)

Creators

  • 1. Inst. of Food Chemistry, TU Dresden (Germany)

Description

After synthesis of fluorine-18 labelled analogues [18F]fluorobenzoylation at the α-amino group, biodistribution and elimination of individual advanced glycation end products, namely Nε-carboxymethyllysine and Nε-carboxyethyllysine, was studied in comparison to lysine in rats after intravenous injection using positron emission tomography. (orig.)

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Part of:
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 2001

Additional details

Publishing Information

Imprint Title
Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 2001
Imprint Pagination
113 p.
Journal Page Range
p. 43
ISSN
1437-322X
Report number
FZR--340

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
35062602
Subject category
S60: APPLIED LIFE SCIENCES; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
EXCRETION; FLUORINE 18; LABELLED COMPOUNDS; LYSINE; POSITRON COMPUTED TOMOGRAPHY; RATS; SYNTHESIS; TISSUE DISTRIBUTION; TRACER TECHNIQUES
Descriptors DEC
AMINO ACIDS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBOXYLIC ACIDS; CLEARANCE; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISTRIBUTION; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; LIGHT NUCLEI; MAMMALS; NANOSECONDS LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOISOTOPES; RODENTS; TOMOGRAPHY; VERTEBRATES

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