Published September 1981 | Version v1
Journal article

Effect of activators of cAMP accumulation on some stages of cell genome expression in the animal body acutely affected by ionizing radiation

  • 1. Kievskij Gosudarstvennyj Univ. (Ukrainian SSR)

Description

A study was made of the template activity of the nuclear chromatin of hepatic and splenic cells of albino rats 2, 12 and 24 h after total-body X-irradiation, and of rats pretreated with radioprotectors - papaverine and serotonin. The radioprotective agents were shown to prevent considerably the inhibiting action of ionizing radiation on the template activity of the spleen chromatin, and to stimulate (serotonin and serotonin+papaverine) the template activity of the liver chromatin in both normal and exposed animals

Additional details

Additional titles

Subtitle (English)
Rep. 2. Effect of serotonin and papaverine on template activity of the nuclear chromatin of hepatic and splenic cells as studied at early times after total-body X-irradiation of rats
Original title (Russian)
Влияние активаторов накопления tsAMF на отдельные этапы экспрессии генома в клетках при остром лучевом поражении организма
Original subtitle (Russian)
Soobshchenie 2. Vliyanie serotonina i papaverina na matrichnuyu aktivnost' khromatina yader kletok pecheni i selezenki krys v rannie sroki posle obshchego rentgenovskogo oblucheniya zhivotnykh.
Augmented title (English)
radioprotective substances: serotonin, papaverine

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
21
Journal Issue
5
Series
Radiobiologiya.
Journal Page Range
654-659
ISSN
0033-8192

Optional Information

Notes
For English translation see the journal Radiobiology (Translation) (USA).