Published February 2018 | Version v1
Journal article

Systemic lupus erythematous associated pitfalls on 18F-FDG PET/CT: Reactive follicular hyperplasia, Kikuchi-Fujimoto disease, inflammation and lymphoid hyperplasia of the spleen mimicking lymphoma

  • 1. Diagnostic Imaging, Cross Cancer Institute, Edmonton (Canada)
  • 2. MUHC Glen Site, Montreal (Canada)
  • 3. MUHC Jewish General Hospital, Nuclear Medicine, Montreal (Canada)

Description

Systemic lupus erythematosus (SLE) is associated with a variety of inflammatory processes that can affect the lymph nodes, brain, kidneys, and spleen. We present two patients with SLE in whom SLE-associated conditions complicated interpretation of 18F-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging of the lymph nodes and the spleen. The imaging findings mimicked lymphoma, but histopathological evaluation showed benign processes including reactive follicular hyperplasia in the lymph nodes, Kikuchi-Fujimoto disease in perisplenic lymph nodes, and inflammatory changes and lymphoid hyperplasia in the spleen

Additional details

Publishing Information

Journal Title
Nuclear Medicine and Molecular Imaging (2010 Print)
Journal Volume
52
Journal Issue
1
Series
17 refs, 6 figs
Journal Page Range
p. 74-79
ISSN
1869-3474

INIS