Published 1977 | Version v1
Book Metadata-only

35S induced dominant lethals in male germ cells of mouse

Creators

  • 1. Osmania Univ., Hyderabad (India). Dept. of Genetics

Description

(CBA female x C3H/He male) F1 males born to 35S (20 μCi) treated animals during major organogenesis period were tested for dominant lethal mutations at maturity. The pre-implantation loss showed an increase from 6.88% in the control to 10.92% in 35S treated animals. Similarly the post-implantation loss has increased from 3.96% (control) to 7.40%. As a result of the increased pre- and post-losses the total loss showed a significant increase (17.51%) in F1 males born to 35S treated animals when compared to controls (10.57%). Thus the results clearly show that 35S is mutagenic in male germ cells of mouse. (author)

Additional details

Publishing Information

Publisher
University of Mysore.
Imprint Place
Mysore
Imprint Title
Proceedings of the L.C. Dunn and Th. Dobzhansky memorial symposium on genetics [held at Mysore during December 16-18, 1976]
Journal Page Range
p. 142-152.

Conference

Title
L.C. Dunn and Th. Dobzhansky memorial symposium on genetics.
Dates
16 - 18 Dec 1976.
Place
Mysore, India.

INIS

Country of Publication
India
Country of Input or Organization
India
INIS RN
10433046
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BEHAVIOR; EMBRYOS; FERTILITY; GENETIC RADIATION EFFECTS; GERM CELLS; INTRAPERITONEAL INJECTION; LETHAL MUTATIONS; MATING; MICE; PREGNANCY; RADIONUCLIDE ADMINISTRATION; SULFUR 35
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; DAYS LIVING RADIOISOTOPES; EVEN-ODD NUCLEI; GENETIC EFFECTS; INJECTION; INTAKE; ISOTOPES; LIGHT NUCLEI; MAMMALS; MUTATIONS; NUCLEI; RADIATION EFFECTS; RADIOISOTOPES; RODENTS; SULFUR ISOTOPES; VERTEBRATES

Optional Information

Notes
37 refs.