Published 1988 | Version v1
Book Metadata-only

In vivo proton MR spectroscopy of canine status epilepticus

Creators

Description

Invasive studies of rodent seizure models have demonstrated twice-normal lactate accumulation at the seizure focus. The authors investigated metabolic changes in canine kainic acid-induced seizures by means of in vivo volume-selective water-suppressed proton MR spectroscopy (MVSTE pulse sequence). Spectra from several experiments are presented demonstrating changes in lactate and MR imaging-visible lipid concentration. Spectra were obtained with interlaced acquisition from the brain and an external standard for relative quantification, with best-case line width of 4 Hz and typical line widths of 7-15 Hz at 1.5 T. Direct injection of NAA and lactate in the brain allowed in vivo identification of resonances

Additional details

Publishing Information

Publisher
Radiological Society of North America Inc.
Imprint Place
Oak Brook, IL (USA)
Imprint Title
Radiological Society of North America 74th scientific assembly and annual meeting (Abstracts)
Journal Page Range
p. 41.

Conference

Title
74. scientific assembly and annual meeting of the Radiological Society of North America (RSNA).
Dates
27 Nov - 2 Dec 1988.
Place
Chicago, IL (USA).

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
20056621
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference, Numerical Data
Descriptors DEI
BRAIN; DIAGNOSIS; DOGS; EXPERIMENTAL DATA; IN VIVO; LIPIDS; NMR IMAGING; NMR SPECTRA; PROTON SPECTRA; SYMPTOMS
Descriptors DEC
ANIMALS; BODY; CENTRAL NERVOUS SYSTEM; DATA; DIAGNOSTIC TECHNIQUES; INFORMATION; MAMMALS; NERVOUS SYSTEM; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANS; SPECTRA; VERTEBRATES