Published 1976 | Version v1
Journal article Metadata-only

Spontaneous and evoked cerebral activity modifications on whole-body γ irradiated adult rabbit

Creators

  • 1. Centre de Recherches du Service de Sante des Armees, Centre d'Etudes Nucleaires de Fontenay-aux-Roses, 92 (France)
  • 2. CEA Centre d'Etudes Nucleaires de Fontenay-aux-Roses, 92 (France). Dept. de Protection

Description

Whole-body γ-exposure from 150 to 850 rads (dose-rate: 14 rads.min-1) delivered to adult rabbits chronically implanted with electrodes resulted in prompt and delayed changes of behavior, arousal and spontaneous and evoked electrical activities. Electrophysiological techniques of polygraphic recording and signal processing showed that the alterations were related to the absorbed dose. The threshold dose accompanied with transient changes of arousal should be in the range of 50-100 rads; below this range, to the exclusion of some possible behavior changes, exposure should act as a stimulation that would become nociceptive at higher doses only

Abstract (French)

L'irradiation γ globale comprise entre 150 et 850 rads (débit de 14 rad.min-1) entraîne chez le lapin adulte muni d'électrodes chroniquement implantées des modifications immédiates et retardées du comportement, de la vigilance et des activités électriques cérébrales spontanées et évoquées. Les techniques electrophysiologiques d'enregistrement polygraphique et les méthodes de traitement du signal permettent d'établir que ces altérations sont reliées à la dose absorbée. La dose-seuil s'accompagnant de modifications transitoires de la vigilance serait comprise entre 50 et 100 rads ; au-dessous de cette gamme de dose, l'irradiation agirait, à l'exclusion d'éventuelles modifications du comportement, comme une stimulation, qui ne deviendrait nociceptive que pour des doses plus élevées.

Additional details

Additional titles

Original title (French)
Modifications de l'activite electrique cerebrale spontanee et evoquee chez le lapin adulte soumis a une irradiation γ globale

Identifiers

DOI
10.1051/radiopro/19761102087;

Publishing Information

Journal Title
Radioprotection
Journal Volume
11
Journal Issue
2
Series
Radioprotection.
Journal Page Range
87-102
ISSN
0033-8451

Conference

Title
Seminar on radiobiology.
Dates
29 Apr 1975.
Place
Fontenay-aux-Roses, France.

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
8281220
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BEHAVIOR; BIOLOGICAL RADIATION EFFECTS; CENTRAL NERVOUS SYSTEM; ELECTRIC CURRENTS; GAMMA RADIATION; RABBITS; RECORDING SYSTEMS; THRESHOLD DOSE; WHOLE-BODY IRRADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; CURRENTS; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; NERVOUS SYSTEM; RADIATION DOSES; RADIATION EFFECTS; RADIATIONS; VERTEBRATES

Optional Information

Notes
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