The middle-long term effect of TAE with pingyangmycin-lipiodol emulsion for hepatic hemangioma

Objective: To evaluate the middle-long term effect of transcatheter arterial embolization (TAE) with pingyangmycin-lipiodol emulsion (PLE) in the treatment of hepatic hemangioma. Methods: Collected 116 hepatic hemangioma cases underwent interventional treatment with PLE in our hospital from April 2000 to September 2010. According to WHO solid tumors reference standard, evaluate clinical efficacy by the reduction rate of tumor; the changes of the clinical symptoms and complications were all recorded in the follow-up data. Results: 139 lesions of 116 cases were treated successfully. Follow-up 6 months to 10 years, the clinical symptoms disappeared in 79 cases, relieved in 6 cases and no change in 2 cases, effective rate is 97.7%. The size of the lesions reduced in different degrees. The effective rate of 6 months to 1 year, 1 to 3 years, 3 to 5 years and 5 to 10 years were 84.2%, 85.4%, 88.1% and 96.4% respectively. The largest cross-sectional areas of long-term follow-up 28 lesions were (30.54±23.98) cm2, (24.89±19.48) cm2, (20.73±17.78) cm2, (17.30±15.21) cm2 respectively, compared with preoperative [(89.44±67.93) cm2] respectively with a significant difference (P<0.05). There were no serious complications in all cases. Conclusion: TAE with PLE in hepatic hemangioma proves to be effective, safe and little side-effects. It has broad indications and is an ideal method in the treatment of hepatic hemangioma. (authors)