Published October 1989
| Version v1
Journal article
45Ca uptake by retinal pigment epithelial cells
Description
Uptake of 45Ca was studied in isolated frog retinal pigment epithelial cells. 45Ca accumulation was found to be a saturable, temperature-dependent event. Kinetic analysis of this accumulation revealed two transport systems with apparent km of 2.0 and 0.3 mM. We found the presence of a Na-Ca exchanger mechanism that releases Ca2 under depolarized conditions. Light induced an increase of 45Ca uptake due to activation of the Na-K-ATPase and consequent decrease of extracellular potassium concentration
Additional details
Publishing Information
- Journal Title
- Investigative Ophthalmology and Visual Science
- Journal Volume
- 30
- Journal Issue
- 10
- Series
- Invest. Ophthalmol. Visual Sci.
- Journal Page Range
- 2114-2117
- ISSN
- 0146-0404
- CODEN
- IOVSD
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21027571
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- ATP-ASE; CALCIUM; CALCIUM 45; ENZYME ACTIVITY; EPITHELIUM; MEMBRANE TRANSPORT; POTASSIUM; RETENTION; RETINA; SODIUM; TEMPERATURE DEPENDENCE; TRACER TECHNIQUES; VISIBLE RADIATION
- Descriptors DEC
- ACID ANHYDRASES; ALKALI METALS; ALKALINE EARTH METALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CALCIUM ISOTOPES; DAYS LIVING RADIOISOTOPES; ELECTROMAGNETIC RADIATION; ELEMENTS; ENZYMES; EVEN-ODD NUCLEI; EYES; HYDROLASES; INTERMEDIATE MASS NUCLEI; ISOTOPE APPLICATIONS; ISOTOPES; METALS; NUCLEI; ORGANIC COMPOUNDS; ORGANS; PHOSPHOHYDROLASES; RADIATIONS; RADIOISOTOPES; SENSE ORGANS; TISSUES