Published December 2019
| Version v1
Journal article
MRI identifies biochemical alterations of intervertebral discs in patients with low back pain and radiculopathy
Creators
- 1. University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology (Germany)
- 2. University Dusseldorf, Medical Faculty, Department of Orthopedics (Germany)
- 3. University of Muenster, Institute of Biostatistics and Clinical Research (Germany)
Description
Key Points
• Molecular intervertebral disc damage was associated with LBP and radiculopathy.• Patients with radiculopathy and LBP demonstrated a depletion of gagCEST values compared with healthy controls.
• GagCEST imaging may be a non-invasive tool for investigation of degeneration processes of lumbar intervertebral discs (IVDs). GagCEST imaging may be an imaging biomarker for biochemical IVD alterations.
Additional details
Identifiers
Publishing Information
- Journal Title
- European Radiology
- Journal Volume
- 29
- Journal Issue
- 12
- Journal Page Range
- p. 6443-6446
- ISSN
- 0938-7994
- CODEN
- EURAE3
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 54094571
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BIOLOGICAL MARKERS; NMR IMAGING; PAIN; PATIENTS
- Descriptors DEC
- DIAGNOSTIC TECHNIQUES; SYMPTOMS
Optional Information
- Copyright
- Copyright (c) 2019 European Society of Radiology