Metabolism of 3H-deoxycytidine and its effect on mouse gonads

The levels of 3H-deoxycytidine binding in mice and rats were shown to depend on the amount of the carrier and the routs of administration, and the dynamics of its retention, on the dose and schedule of its administration. As estimated by the criterion of the tests mass decrease the 3H-deoxycytidine dose of 37 kBq/g is equivalent to γ-radiation dose of 0.06 Gy. The coefficient of 3H-deoxycytidinbe absorption from the digestive tract of mice and rats is 2-10 times as high as that of 3H-thymidine, while both compounds administered to rats transcutaneously have the same absorption coefficients ammounting to 0.02