Published 1995
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Consequences of gamma-irradiation on inflammatory cytokine regulation in human monocytes/macrophages
Creators
Description
Inflammation is a frequent radiation-induced damage, especially after therapeutic irradiation. In this study, we have investigated, the inflammatory cytokine regulation after ionizing irradiation of monocytes/macrophages from four donors. Semi-quantitative RT-PCR revealed, after in vitro 24 h-differentiated monocytes irradiation between 5 to 40 Gy, no induction of interleukin-Iβ (IL Iβ), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α mRNA expression. Moreover, protein quantitation shows no significant increase of post-irradiation secretion. (author)
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Additional details
Additional titles
- Original title (French)
- Consequences de l'irradiation gamma sur la regulation des cytokines de l'inflammation dans les monocytes/macrophages humains
Publishing Information
- Imprint Title
- Scientific works of research workers of the army health service
- Imprint Pagination
- 317 p.
- Journal Page Range
- p. 17-18.
- Report number
- SSA--1996-17
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 29006778
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; GAMMA RADIATION; INFLAMMATION; MACROPHAGES; MONOCYTES; RADIATION INJURIES; RADIOBIOLOGY; RADIOINDUCTION; RADIOTHERAPY
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGY; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DISEASES; ELECTROMAGNETIC RADIATION; INJURIES; IONIZING RADIATIONS; LEUKOCYTES; MATERIALS; MEDICINE; PATHOLOGICAL CHANGES; PHAGOCYTES; RADIATION EFFECTS; RADIATIONS; SOMATIC CELLS; THERAPY
Optional Information
- Notes
- Imprint:6 refs. ;Travaux scientifiques des chercheurs du service de sante des armees.