Published 1989
| Version v1
Journal article
Preparation of carrier-free 11C-amino acids by insertion of hot 11C-atoms into valine and 2-aminobutyric acid with retention of optical asymmetry
- 1. Giessen Univ. (Germany, F.R.). Strahlenzentrum
- 2. Universitaet Giessen (Germany, F.R.). Biochemisches Inst.
Description
Irradiation of optically active crystalline amino acids as targets in the bremsstrahlung of a 65 MeV linear electron accelerator results, among other things, in the production of amino acids with one 11C-atom inserted. The chirality of the compound produced is retained. Separation of these amino acids is possible within 20 min by means of preparative high pressure liquid chromatography (HPLC). (author)
Additional details
Publishing Information
- Journal Title
- Applied Radiation and Isotopes
- Journal Volume
- 40
- Journal Issue
- 7
- Series
- Appl. Radiat. Isot.
- Journal Page Range
- 637-640
- CODEN
- ARISE
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 21001789
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- AMINO ACIDS; CARBON 11; CHEMICAL PREPARATION; LABELLING; LIQUID COLUMN CHROMATOGRAPHY; RADIOPHARMACEUTICALS
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CARBOXYLIC ACIDS; CHROMATOGRAPHY; DRUGS; EVEN-ODD NUCLEI; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES; SYNTHESIS